Disposable Medical Supplies Hyaluronic Acid Injection Knee Relief Knee Pain

Product Description

Product Description

Singjoint®, is a kind of colorless transparent liquid gel which is made of hyaluronic acid, from streptococcal fermentation metabolites.

It is indicated for the treatment of symptoms of osteoarthritis of knee. By replacing and supplementing the pathological synovial fluid in the osteoarthritic joints, it reduces pain and improves joint function.

Features	SingJoint®	SingJoint® Plus
Ingredient	HA	HA
Source	Biofermentation	Biofermentation
Molecular weight	≥1.0 Mda	≥1.6Mda
Concentration	10mg/ml, 12mg/ml	20mg/ml
Volume	1.0ml, 2.0ml, 2.5ml	2.0ml, 3.0ml
Total HA Concentration	10mg-30mg	40mg, 60mg
Type of HA configuration	Linear	Linear
Monthly administration	3 - 4 injection, once a week for 3 to 4 consecutive weeks.	1 Injection
Duration	Up to 6 months	6 months+
CE	Yes	Yes
Safety	Safe	Safe
Clinical studies	Yes	Yes
Sales coverage	90+	90+

SingJoint® Advantages

Better Patient Compliance:

excellent biocompatibility due to 

bio-fermentation, no immunogen, biodegradable.

 

Effective: 

High Concentration of HA: Creating a high viscosity environment to replicate healthy joint function.

High Molecular Weight 

Long lasting pain relief

Delay total knee replacement (TKR) surgery

 

Convenient:

Administered in doctor's  office

Why Choose Singjoint?

1.Higher Concentration, Stronger Support

Singjoint's hyaluronic acid (HA) has an higher concentration of 102%, significantly higher than the Turkey Brand S. 

For example, for 3.0ml-30mg/ml, Turkey Brand actually just has 90*87.1%=78.39mg).

2.Better Biocompatibility for a Comfortable Experience

With an osmolality of 313 mOsm/kg closely matching that of the human body, Singjoint® offers superior biocompatibility. This means minimal discomfort during injection and smoother integration for natural-feeling relief.

3.Longer-Lasting Performance

Singjoint's kinetic viscosity is 5/10 times that of competing products, and its viscosity-average molecular weight is nearly double that of competing products. These key indicators mean that Singjoint takes longer to degrade, extending the effectiveness of every injection.

In addition, a single injection of Singjoint® delivers efficacy that lasts for up to 6 months, significantly longer than the competing product (only 3-4 months).

What is Osteoarthritis (OA) of  the Knee?

Knee joint is lubricated by synovial fluid, which contains hyaluronic acid and acts as the knee's shock absorber and protects cartilage coverings from wear and tear.

With OA of the knee, less synovial fluid is produced naturally in the knee joint. Gradually, as joint fluid continues to break down and cartilage deteriorates, bones may start to rub against each other, leading to pain, stiffness, swelling and limited joint activity. 

Why is Hyaluronic Acid Injection Effective for Osteoarthritis?

HA is a natural  mucopolysaccharide in synovial fluid and is the major and most important component;
High viscoelasticity, lubricity, physical alterability of HA provide better lubrication and shock absorption;
The properties of the synovial fluid are dependent on the concentration of HA and its molecular weight.

Exogenous HA can enhance chondrocyte HA synthesis, prevent the degradation of cartilage and promote its regeneration. Moreover it can reduce the production of proinflammatory mediators and matrix metalloproteinases involved in OA pathogenesis.

FAQ

Q: What happens after the injections?

A: You can resume normal day-to-day activities immediately after the injections, but you should avoid any excessive activities for about 48 hours.

 

Q: What are the adverse reactions of SingJoint® injections?

A: Mild transient local pain, swelling, arthralgia and joint stiffness at the injection site are reported after intra-articular injections. These symptoms are generally mild and transient. They usually resolve within 2 to 7 days without medical intervention. If symptoms are persistent, please consult with your treatment doctor.

 

Q: How quickly will SingJoint® work?

A: You may not notice any benefits immediately after the first injection but you should start to feel less pain and stiffness over the next few weeks.